OC02 - Clinical Treatment and Interventions -1

Lower Sleep Disturbance Scores at Baseline Predict Improvements in Suicide Ideation Post-treatment in Individuals Enrolled in a Randomized Controlled Trial
August, 29 | 12:00 - 13:00

Sleep disturbance is a known suicide risk factor. A 2012 meta-analysis found that sleep disturbance is significantly associated with an increase in relative risk for suicidal ideation (SI), suicide, and suicide attempt ranging from 1.95 (95% CI, 1.41-2.69) to a relative risk of 2.95 (95% CI, 2.48-3.50) in unadjusted studies. Similarly, sleep disturbance has deleterious impacts on cognitive functions implicated in problem-solving and emotion regulation, suggesting that individuals experiencing sleep disturbance may be more vulnerable to experiencing more severe or prolonged SI. The present study examines whether baseline sleep disturbance scores moderated trajectories of SI improvement following receipt of evidence-based therapy for suicide risk reduction when delivered via telehealth. Participants were 64 adults with past week SI or past month suicide attempt who enrolled in this telehealth trial for high-risk individuals. Eligible and consented participants were randomized to receive one of two evidenced-based treatments for suicide risk reduction: Brief Cognitive Behavioral Therapy (BCBT) and Present Centered Therapy (PCT). All participants completed the Patient-Reported Outcomes Measurement Information System (PROMIS) measure of sleep disturbance at baseline, and the Scale for Suicide Ideation at baseline, 3-, 6-, and 9-month follow-ups. A Mixed-model RMANOVAs was conducted to examine changes in SI severity over time as a function of baseline sleep disturbance, controlling for relevant covariates (i.e., treatment group). Within the full sample, SI did not change significantly from baseline to 9-month follow-up (F(3, 49) = 0.45, p =.72, ?p2 = .03), regardless of treatment group. However, baseline sleep disturbance scores significantly moderated the degree of change in SI over time (F(1, 51) = 4.43, p <.05, ?p2 = .08), such that lower sleep disturbance scores were associated with greater reduction in SI from baseline to 9-month follow-ups (r=-.30, p<.05) These findings suggest that individuals who have lower sleep disturbance at the beginning of treatment demonstrate greater improvements in SI over time. Findings can inform further research and clinical intervention on the relationship between sleep disturbance and SI, and the significance of targeting sleep improvement in treatments that seek to reduce SI.

Speakers