Borderline personality disorder (BPD) is a debilitating condition characterized by pervasive instability across multiple major domains of functioning. The majority of persons with a BPD diagnosis engage in self-inflicted injury and up to 10% die by suicide – rendering persons with this condition at exceptionally elevated risk of premature mortality. Better characterization of clinical risk factors among persons with BPD who die by suicide is urgently needed. For the present study, we examined patterns of medical and mental illness diagnoses among persons with BPD who died by suicide via a population-based data resource and biobank (The Utah Suicide Mortality Risk Study). We compared these individuals to three other groups: (1) persons who died by suicide without a history of BPD, (2) persons still living with a history of BPD diagnosis, and (3) persons who died by suicide with a different personality disorder diagnosis. We identified 379 suicides among persons carrying BPD diagnostic codes (International Classification of Diseases [ICD] 9 301.83 & ICD10 F60.3), 280 age- and sex-matched persons living with BPD; 9,468 suicides among persons without BPD diagnostic codes, and 589 suicides among persons with another personality disorder diagnosis. Diagnostic data (ICD 9 & 10 codes) were aggregated into >1,580 clinical phenotypes (Phecodes) and compared using multivariable logistic regression models accounting for age, sex and transformed number of diagnostic codes with Bonferroni correction. We found significant differences between persons with BPD who died by suicide and all other comparison groups. Study results may aid us in identifying high-risk subtypes and targeted intervention approaches among persons with BPD.