PS50 - People Who Live With Psychosis: From Suicide-Theory to Suicide-Therapy in Some of the Most Vulnerable

The Dynamic Interplay Between Interpersonal Relationships and Suicidal Experiences in People With Non-affective Psychosis: Findings From the CARMS (Cognitive Approaches to Combatting Suicidality) Project
August, 31 | 08:30 - 10:00

Introduction: Suicidal experiences are substantially more frequent and more severe in people with non-affective psychosis (e.g., hallucinations, delusions and paranoid feelings). It is important to understand pathways to suicidal experiences from psychosocial perspectives in order to develop robust mechanistic models which form the foundation for the development of suicide-focused psychological interventions. Perceptions of social isolation, loneliness, and interpersonal relationship problems are central to the pathways which lead to suicidal experiences. However, the ways in which these negative appraisals lead to suicidal experiences is still poorly understood, especially in people with non-affective psychosis. The CARMS project attempted to redress this gap. Methods: CARMS tested the efficacy of a suicide-focused cognitive therapy for people with psychosis (CBSPp) using a two-armed RCT (CBSPp+TAU versus TAU) with assessment timepoints at baseline, 6- and 12 months. Participants had non-affective psychosis plus recent suicidal experiences. Qualitative work-streams were nested within the RCT. We describe convergent findings using both quantitative and qualitative methods and analyses from CARMS. Results: The first set of findings are quantitative. A significant mediated, indirect, treatment effect was found, in which our suicide-focused therapy significantly reduced the severity of suicide thoughts at six months relative to baseline compared to a control (TAU) group because it strengthened positive appraisals of social support from friends, family, and other people. The direct effect was not significant. The second set of findings build on the first and are based on cross-sectional qualitative one-to-one interview data analysed with reflexive thematic analysis. A complex dynamic is evident illustrated by themes of i. mattering “if I kill myself who's going to miss me”, ii. connectedness “socialising is a part of everything really, you can't be alone all the time”, and iii. sharing “And with friends and my boyfriend there’s just no understanding”. Discussion: The mediational pathways and the qualitative findings converged in that perceptions of social support and being feeling connected to other people acted to counter suicidal experiences, with perceptions of social support being a mediator of the therapeutic treatment effect. However, interpersonal relationships with other people can also present myriad complexities which can feel hard to navigate.

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