Introduction Findings about the association of suicidal behavior in mid- and late life and individual personality traits remain inconsistent, suggesting that suicidal behavior is likely associated with several constellations of risk scores across multiple dimensions of personality. Methods We conducted a latent profile analysis (LPA) in 109 suicide attempters aged ?40 years (mean=61 years, SD=8), based on the following personality traits: the Big Five (NEO-Five Factor Inventory), grandiose narcissism (Brief Pathological Narcissism Inventory), and intolerance of uncertainty (Need For Closure Scale). Results Pairwise Pearson correlation coefficients between traits were mild to moderate. The best LPA solution, with equal variances and covariances of the traits within each profile, yielded three attempter profiles (entropy = 0.86), which we described as Callous Narcissistic (n=25) - highest on grandiose narcissism and lowest on agreeableness; Extraverted Rigid (n=13) - highest on intolerance of uncertainty, extraversion, and agreeableness; and Careless Labile (n=71) - highest on neuroticism and lowest on conscientiousness. Compared to non-psychiatric participants (n=93) and depressed non-attempters (n=126), Callous Narcissistic attempters remained highest on grandiose narcissism and lowest on agreeableness, Extraverted Rigid attempters were highest on intolerance to uncertainty and comparable to non-psychiatric participants on extraversion, and Careless Labile attempters were highest on neuroticism and comparable to depressed non-attempters on conscientiousness. Regarding clinical characteristics, bivariate analysis indicated that Introverted Labile attempters were younger than all other groups and had more borderline traits. Extraverted Rigid attempters had more cognitive deficits than all other groups except for Callous Narcissistic attempters and were older than other attempter profiles at both their first and most recent attempt. Intent and planning at the most lethal attempt were highest in Callous Narcissistic attempters. Discussion Our findings corroborate that attempters with early- and late-onset suicidal behavior have different personality profiles and attempting styles. Cognitive deficits paired with a rigid personality style may result in suicidal behavior in older age, whereas narcissistic traits and callousness may lead to particularly high determination to die. Future research should look at prospective associations with suicide risk of the outlined profiles.